Posted by yxibow on March 19, 2007, at 15:33:57
In reply to Re: akathisia versus anxiety, Ken Blades?, posted by naughtypuppy on March 19, 2007, at 10:01:11
> I would best describe akathisia as a restless feeling so bad that you wanted to crawl out of your own skin. I have experienced it with a combination of AD's and Diphenhydramine. The worst though, was in the early 70's when it was trendy to put some one with anxiety on antipycotics such as haloperidol. Amazing that the psyciatric community keeps repeating the same things over and over again. I believe that Albert Einstein said somthing to the effect of "Insanity: doing the same thing over and over again and expecting different results".
>
Well, EPS remains the bane of neuroleptics for disorders that in many cases unfortunately must be treated with them, namely schizophrenia where the patient or others are in danger of harm.Don't think the scientific community has tried to get away from it.
Atypicals were first surmised to not have this issue, unfortunately they do. However, the first atypical, Clozaril, had nearly none but has other potentially -bad- side effects. It still remains a "gold" standard for treatment resistant schizophrenia though as even if it does not produce much EPS, it is a strong antipsychotic.
Its hard to believe that one would get akathisia from diphenhydramine since IV Benadryl remains one fairly quick fix for in-hospital treatment of akathisia with agents that are either neuroleptics or are but are generally not used for psychosis (Compazine), but I guess there are idiosyncratic reactions in anybody.
poster:yxibow
thread:741810
URL: http://www.dr-bob.org/babble/20070314/msgs/742182.html