Posted by med_empowered on March 19, 2007, at 15:30:41
In reply to Mode of action, MPH (Ritalin) and Buproprion., posted by Brutus1 on March 19, 2007, at 11:16:27
Wellbutrin is pretty stimulant-ish (its like a mild version of Tenuate), but I think there differences. For one, b/c of the reuptake inhibition, wellbutrin reduces dopamine release, which is something a lot of ADs do. This is also why you can sometimes combine it with antipsychotics w/ good results. MPH does reuptake inhibition but, as far as I know, doesn't have any major impact on dopamine release. Its also sometimes used in schizophrenia, with stable patients with a lot of negative symptoms, or stable patients mired in drug-induced sedation (like with clozapine).
poster:med_empowered
thread:742117
URL: http://www.dr-bob.org/babble/20070314/msgs/742180.html