Posted by Quintal on February 17, 2007, at 19:35:46
In reply to Why Most New Antidepressants Are Ineffective, posted by bulldog2 on February 17, 2007, at 13:07:07
That's an excellent link bulldog. I particularly agree with him about Parnate being one of the most effective antidepressants, yet one of the most poorly researched. It was an interesting read and very encouraging for someone in my position.
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The major remaining alternative drug treatment to remember is the old MAOIs, particularly tranylcypromine. Ironically, that is the one drug for which there is the very least amount of controlled trial evidence, yet the one drug that most experienced psychopharmacologists agree is indispensable for the treatment of severe illnesses. I would submit that this is yet another major example of the unhelpfulness of controlled trials of medication and the bias produced by pharmaceutical company sponsorship in the perceived relative effectiveness of treatments. In my opinion tranylcypromine is the most under-used antidepressant available. It is the one I would take, and the one I would give to my nearest and dearest, if any of us became ill. The supposed problems and ‘dangers’ of MAOIs are greatly exaggerated (see my information on MAOIs), In my opinion, to the point of hysteria.
Is there anything you can do if you want to learn about what antidepressant treatment strategies actually do work? I suggest my essay on dual action antidepressants is a good place to start.
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Q
poster:Quintal
thread:733613
URL: http://www.dr-bob.org/babble/20070213/msgs/733687.html