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Remeron and receptors

Posted by saturn on February 13, 2007, at 21:50:02

Is it correct that Remeron first hits H1, then 5-HT2 and 5-HT3 and then later on alpha-1 NE?

I'm wondering if the following might be about right:

7.5 mg---mainly H1 blocked
15 mg---H1 and 5-HT2/5-HT3 blocked
30 mg and up---H1, 5-HT2/5-HT3 and NE alpha-1 blocked?

Also, does Remeron increase synaptic serotonin at all or are the serotonin effects just the 5-HT2/3 antagonism?

Thanks...Peace...Saturn.

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poster:saturn thread:732596
URL: http://www.dr-bob.org/babble/20070213/msgs/732596.html