Posted by psychobot5000 on February 4, 2007, at 12:46:37
In reply to Re: Parnate and AD effect- » psychobot5000, posted by NYCguy on February 4, 2007, at 5:15:33
Something over a week, I suppose, and I've backed off to 10 mg. I'd take more, but MAO inhibiton seems to overstimulate some part of my brain and keep me from sleeping, as well as giving me a strange foggy sensation that keeps me from thinking. But the low dose does seem to help somewhat, with few side-effects. (I take tianeptine too, and have occasionally been taking ativan for sleep lately).
> Thanks for the info. Good luck on your Parnate journey! Might I ask how much of a dose you are taking and how long you've been on it?
>
> >
> > My personal experience with Parnate (I also just started) is that there's definitely an independent antidepressant effect, besides the stimulant one. The evidence (and conventional opinion among psychiatrists) seems to back that up. I wouldn't get disheartened--maybe you just haven't had enough weeks on it to get that full AD effect, yet.
> >
> > I do believe that you get better MAO inhibition by spreading the doses out over the day, though. That way your blood-levels of the drug are high, and constantly snapping up MAO. Since that's the presumed mechanism behind the AD effect, it seems the best dosing strategy--assuming you don't get insomnia. It's one of the best! Don't lose hope after just a couple of weeks! But as for me, I say don't sell parnate's stimulant effect short--no doubt here that it's helping me.
> >
> > Best wishes!
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poster:psychobot5000
thread:729076
URL: http://www.dr-bob.org/babble/20070201/msgs/729641.html