Posted by dessbee on January 11, 2007, at 7:31:16
In reply to Re: BDNF - how do you raise your levels?, posted by ronaldo on January 11, 2007, at 6:00:47
In animal models they use alternate-day-fasting.
Rats on periodic fasting exhibited increased levels of Heat Shock Protein-70 (HSP-70) and Glucose Regulated Protein-78 (GRP-78). These protein chaperones can protect neurons against excitotoxic and oxidative stress, suggesting that their increased levels contribute to the neuroprotective effects of periodic fasting. In addition to the above, studies have documented activities of several other neuroprotective factors such as nerve growth factor, brain derived neurotrophic factor (BDNF), fibroblastic growth factors and IGF1.
Another benefit from intermittent fasting is improved insulin sensitivity (low insulin levels).Mark Mattson, a neuroscientist at the National Institute on Aging in Baltimore is one of the leading scientists in this area. I beleive he himself is on a calory restriction diet (30 percent fewer calories daily) where he only eats during a 2-3 hour period every evening.
poster:dessbee
thread:721084
URL: http://www.dr-bob.org/babble/20070107/msgs/721286.html