Posted by SLS on November 22, 2006, at 7:11:22
In reply to Re: Nardil - hopeful » SLS, posted by tensor on November 22, 2006, at 6:48:46
I double-checked the interaction between Zoloft and Wellbutrin on a CYP450 website. It stated that the increase in blood levels of Wellbutrin were substantial: + 75-150% change in exposure to the drug. I guess it makes sense to begin at 75mg and increase gradually from there.
Zoloft inhibits CYP450 2B6, which is a major route of metabolism of Wellbutrin and its hydroxy- metabolites.
- Scott
poster:SLS
thread:706075
URL: http://www.dr-bob.org/babble/20061117/msgs/706094.html