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Re: SSRI dopamine issues. » Phillipa

Posted by SLS on October 1, 2006, at 22:19:29

In reply to Re: SSRI dopamine issues., posted by Phillipa on October 1, 2006, at 18:33:30

> I wonder how many people will go off SSRI's after reading this?Love Phillipa


I hope none just yet.

I am concerned that there is a problem with SSRIs producing EPS in a very small percentage of people. I am very interested to know more about the biology behind these phenomena.

Did you know that EPS is listed as a potential rare side effect on the label for Prozac? No conspiracy theories yet? That's good.

Extrapyramidal side effects are not the same as the induction of a degenerative disease process like Parkinsons. As far as developing motor tics or dyskinesias, I think we should have been seeing more of this after 20 years of Prozac if it were going to be a problem.

It is easy to accuse a drug of being potentially dangerous by saying we don't know what its long-term effects will be. You can say that about so many drugs. With Prozac and friends, we seem to have an infrequent or even rare side effect of EPS and the reversible worsening of Parkinsons. I don't feel we can yet extrapolate that data into concluding that these will result in future cases of Parkinson's Disease, dystonias or other movement disorders, motor tics or Tourettes, or tardive dyskinesia. Let's look at it. Let's be careful what we become confident in concluding before we take away effective drugs out of people's hands.


- Scott

 

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