Posted by ace on September 29, 2006, at 22:01:17
In reply to Re: Pros and Cons of Seroquel low dose, posted by fca on September 29, 2006, at 20:27:02
> ACE's response is over my head and I am reluctant to recommend a specific drug regime. I think what he says about TCAs and MAOIs effectiveness may be true but he does not mention side effects and discontinuation rates (generally lower for SSRI).
True. I have noticed that GENERALLY SSRI's have more benign s/effect profiles - but certainly not in the whole population!
Clinical studies have showed over and over the vast superiority of TCA's & MAOI's over the newer SSRI. This material has tried to be quashed by certain drug companies.
However, TCA and MAOI drugs DO indeed usually have more s/eefects and take longer- sometimes years- to go.
Also, I think most physicians would be reluctant to start TCAs or MAOIs without a thorough trial on SSRIs.
This really annoys me!!!!! Shipko MD has widely claimed (with clinicals studies to support hisa claims) the fact that SSRI's contribute to depletion of DOPAMINE IN THE SUBSTANTIA NIGRA. This is a fancy name for a part of the brain which, in horizontal sections, looks like two dark whiskers....contains DA neurons....we loose 60% of DA naturally....now, it is possible that we are going to see in years to come a lot of ex SSRI long time users with Parkinsons d/ease.
But please research and draw your own conclusuions. I personally agree with Shipko.
Well, that has nothing to do with seroquel--my daughter who is alcoholic with an ED finds it to be an exrtremely reliable anxiolytic at low dose.
Very true. But has she tried any Benzos??
She takes prn at this point. Preferable for her because of substance abuse history--loves benzos but recognizes this is not a wise choice for her,Very wise decision....benzo's + substance abuse is not a good mix!
Take care!
Ace
poster:ace
thread:690091
URL: http://www.dr-bob.org/babble/20060927/msgs/690364.html