Posted by blueberry on September 16, 2006, at 8:51:05
In reply to What all meds have you tried ? (nm), posted by linkadge on September 16, 2006, at 7:52:51
paxil
zoloft
prozac
serzone
remeron
effexor
cymbalta
moclobemide
milnacipran
nortriptyline
desipramine
buspar
pindolol
modafinil
adrafinil
adderall
ritalin
seroquel
zyprexa
amisulpride
xanax
klonopin
lorazepam
depakote
lamictal
lithium
st johns wort
rhodiola rosea
ginkgo biloba
fish oil
5htp
dl-phenylalanine
l-phenylalanine
d-phenylalanine
tyrosineI'm tired of being a chemistry lab.
Even when something works, the relapse rate is 100%.
Most of the above things resulted in a worsening of depression. A small few of them resulted in improvements that were brief. All of them interfered with the ability to work and function. All of them came with intense side effects that were at least as crippling as the depression itself.
The best of all was prozac+st johns wort+zyprexa, but it pooped out in 2 months.
I am aware that the 70% to 80% of people who did well with ECT are not hanging out at pbabble, so this thread is a bit skewed to the negative side. We don't hear at all from the 80% who did well because they are out living life.
Hopefully ECT will work...and since my depression is extreme in the morning and not bad at all in the evening I have a hunch it is of a stress hormonal cyclical nature that responds well to ECT. Also, clinical studies show that people who had depressions as a result of ecstacy use (damaged serotonin synapses) that were unresponsive to ssri's and snri's got well with ECT. I never did ecstacy, but I have had short periods of cocaine, PCP, mescaline, amphetamine, long periods of marijuana, and not to mention all the psychiatric drugs mentioned above...who knows what long term damage or modifications they do to synapses and such. Of course, I am aware I could say the same about ECT.
There is still room for me to have second thoughts and back out. But really, how many more years of trials does one need before exploring something else that has a good possibility of helping.
Bottom line...we're talking suicidal depression here. I have had not one but two second opinions. All seem to agree this is not the time to keep messing around with meds.
poster:blueberry
thread:686296
URL: http://www.dr-bob.org/babble/20060909/msgs/686500.html