Posted by SLS on September 14, 2006, at 9:00:40
In reply to Re: Glutamatergic neurotransmission and mood disor, posted by linkadge on September 14, 2006, at 8:41:40
> I think that certain aspects of the monamine theory are usefull. For instance, while a direct monoamine imballance may not be evident, that is not to say that current antidepressants can't ameliorate certain aspects of certain mood disorders.
I agree.Perhaps hitting targets upstream can produce a cascade of events that alter pathologies downstream. Symptom clusters might be ameliorated by hitting targets downstream. Who knows if there even is a single target between the upstream and downstream to aim at. In my case, I think there is. Mood shifts are so rapid and complete, it is difficult to believe that multiple systems containing second-messenger system-mediated events could possibly contribute. 'Tis a puzzlement.
- Scott
poster:SLS
thread:685302
URL: http://www.dr-bob.org/babble/20060909/msgs/685846.html