Posted by linkadge on September 14, 2006, at 8:41:40
In reply to Re: Glutamatergic neurotransmission and mood disor, posted by SLS on September 14, 2006, at 0:39:35
I think that certain aspects of the monamine theory are usefull. For instance, while a direct monoamine imballance may not be evident, that is not to say that current antidepressants can't ameliorate certain aspects of certain mood disorders.
For instance, in many mood disorders, metabolism in the prefrontal cortex is diminished. Certain antidepressants can improve that. Activity in the lower brainstem too, may be overactive or underactive, and certain drugs can change that.
It is important to look at other parts of the brain, and not only the hippocampus.
Can, for instance, will targetting *just* the hippocampus change other symtoms like psychomotor retardation etc?
Linkadge
poster:linkadge
thread:685302
URL: http://www.dr-bob.org/babble/20060909/msgs/685836.html