Posted by SLS on August 13, 2006, at 13:10:29
In reply to Re: Sibutramine (Meridia) - Day 8 » SLS, posted by Racer on August 13, 2006, at 12:31:47
> Scott, I know you have a history of responding for a couple of days, only to lose the response. Have you ever had it the other way around? That you feel worse for a few days as you titrate up, but get a better response later in treatment?
Actually, my most recent trial of Wellbutrin followed that sort of pattern. It produced some mild dysphoria for about a week before I responded well to it.
> Do you think there's a chance of such a thing happening this time around?
Yes. I have this very silly little piece of brain tissue that always thinks there's a chance of something good happening. After all this time, I don't know why.
> You know I'm really pulling for you on this one, and you know why, so I admit freely that I'm biassed in favor of giving it a good chance...
Much of the dysphoria that I experienced this morning seems to have passed. There is still a little there, but that I am not feeling worse is a good thing.
> Still, I'm sorry you're not having a great ride. I hope it gets better.
Thanks.
> Remind me again: have you ever had a good response that lasted for any length of time?Yes. In 1987, at age 27, a combination of Parnate 60mg and desipramine 150mg produced a complete remission that lasted six months until the drugs were discontinued due to the appearance of mania. After being without medication for two months, I relapsed into depression. Without getting into the particulars of what transpired subsequently, I no longer respond to the same combination.
- Scott
poster:SLS
thread:673646
URL: http://www.dr-bob.org/babble/20060810/msgs/676035.html