Posted by Jost on August 5, 2006, at 12:32:47
In reply to Re: What stage of treatment-resistance are you?, posted by nickguy on August 4, 2006, at 15:58:36
SSRI: prozac, zoloft too sick to go more than three weeks and that was a huge effort):
SNRI: effexor also made me sick
Remeron (1 night) out cold in about three minutes, and slept for about 16 hours, felt awful, pdoc didn't want to try higher dose
Trazadone also sick
SNRI: cymbalta worked a little, but could only take v. low dose every other day, because more made me sick (serotonin syndrome), so somewhat better than nothing--had to stop about three months, because of other adverse reaction
MAOI : Parnate, worked somewhat, but made me feel so tired that, in retrospect, I' was functioning at a very low level, both mentally and physically. Couple of Ts I saw thought I had possible brain malfunction (?) and suggested neuropsych work-up. When the second one saw me after I stopped Parnate, said it must have been Parnate, because I seemed totally different.
Stopped doing a lot of things, because I was sleeping all day, and 10 hours a night, waking up and needing hours more sleep- but I guess just helped me feel less bad-- but again had adverse reaction eventually and had to stop
Welbutrin worked a little, not enough to be adequate AD effect, but also somewhat better than nothing
TCA never tried, my pdoc doesn't like them, and didn't think I would do well on them, after other reactions
now on Emsam.
So, SSRI, SNRI, Trazadone, Remeron--didn't work (or didn't work much)
MAOI (Parnate) not sure if it worked, or I was so wiped out, I didn't have energy to remember how I felt-- wouldn't do it again
If Emsam doesn't work, I'd probably try Welbutrin, and see if I could keep my head somewhat above water until something else comes out, if it does; or I might try combination of adderal and benzo--not sure
Won't ever do ECT, probably won't ever do TCA, unless new ones come out with fewer SE, and less effect on serotonin
My problem--possibly toxic reaction to anything that boosts serotonin too much, or out of proportion to other neurotransmitters.
Don't know how you would stage that.
Jost
poster:Jost
thread:673609
URL: http://www.dr-bob.org/babble/20060802/msgs/674008.html