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Re: What stage of treatment-resistance are you? » linkadge

Posted by SLS on August 5, 2006, at 7:01:50

In reply to Re: What stage of treatment-resistance are you?, posted by linkadge on August 5, 2006, at 3:48:34

> Somewhere at stage 4. I didn't fail and MAOI, I just couldn't take it for long enough. Had a spontainious hypertensive crisis, and have since been refused a subsequent trial.
>
> Parnate was kindof scarry though. (Intense), I don't know if Nardil is any lighter.

In some ways, Nardil is a lighter, more pleasant experience. Marplan is even more so, but is often thought of as a less effective drug. I guess that depends upon who you ask. If you really want to force the issue, I would try Nardil first, and then decide between Emsam and Marplan. Use Emsam is low energy is a major component of your illness. Marplan might be a better "mood-brightener", as is Nardil.

You *appear* to be doing better now than you had been in years previous. I know you have abstained from major antidipressants over this recent period. Perhaps reuptake inhibitors are not the way to go for you.

MAOIs are in some ways cleaner than reuptake inhibitors. Perhaps neurons are not forced to depolarize when no signal is to be propagated with these drugs. There is less noise. They might act more as amplifiers. Who knows? (Not me). If there comes a time when you wish to revisit antidepressant medication, and nothing new has captured your interest, you might want to go with one of the other MAOIs.

Maybe it will be a cannabinoid that gets us both well...

I wish you nothing but the best.


- Scott

 

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