on local DNA scarring

Posted by pseudoname on July 2, 2006, at 11:23:32

In reply to very interesting » capricorn, posted by pseudoname on July 2, 2006, at 10:58:03

> Why does it affect just BDNF creation? Why doesn't the hypermethylation shut down protein production generally?
“The underlying mechanisms for the initiation and targeting of ectopic hypermethylation are not known, although it has been suggested that DNMTs [the chemicals that control methylation] may preferentially bind to damaged or mismatched DNA.”
–DNA hypermethylation http://www.humpath.com/article.php3?id_article=1931
“…the establishment of DNA methylation patterns [is] a long-standing mystery in epigenetics.”
–histone methylation http://www.humpath.com/article.php3?id_article=8552
My confusion feels more tolerable now.

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Damaged DNA:Depression's hidden culprit?? capricorn 7/2/06
very interesting » capricorn pseudoname 7/2/06
on local DNA scarring pseudoname 7/2/06
Re: very interesting » pseudoname Phillipa 7/2/06
Re: very interesting linkadge 7/2/06
I dunno. I wonder too. (nm) » Phillipa pseudoname 7/2/06
Re: very interesting rod 7/2/06
Re: very interesting capricorn 7/2/06
Re: very interesting » capricorn rod 7/3/06

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