Posted by Paulbwell on June 3, 2006, at 4:25:29
In reply to Re: opioids for depression, posted by linkadge on June 3, 2006, at 1:16:06
> Hey, I'm looking for answers too. I'm not too proud to admit that.
>
> It is possible that there is something physically or chemically different about a depressed person's brain. We don't really have any evidence to suggest that the current medications are acutally correcting that abnormality.
Hi Ya,Of course the SSRI's SSNRI's MAO's TCA'a, ETC DON"T 'correct' brain chemistry-they chemically alter it, sometimes making the wearer of that brain feel better-often not. The human Brain is far to complex for 'correcting imballances' in medicine~2006.
That said, and getting back onto the title topic, I'm no Opi' addict, but have experimented with Morphine IR@SR, Dihydrocodeine, Codeine, in different forms of administrating.
Since 1958 when Imipramine (the first AD came out) medicine has focused on increasing Serotonin, Dopamine, Norephinephrine, with thes meds over the last 40+ years.
Perhaps, just perhaps some mood disorded folk have an imbalance in their brains Endorphin system? (troublesome to face by the med professional i know).
I myself have had potent AD responses from MSIR @Codeine tabs. Aposter here Jerry is LEGALLY scripted 5mgs Hydrocodone (Vicodin) 4x daily, and attributes it to his higher functioning/mood.
Remember Opiods/iates were often given for 'Psych' issues before the biopsychiatric theories of the 1950's~came to the fore, hell, in the early 1900's you could go into ANY drugstore and buy OTC effective dosages of, Opium, Morphine, Cocaine, Heroin, products, designed to 'treat' any ails you could think of.YES Opiates/oids do indeed help depressed mood states, in many, with little SE's relatively
Cheers
poster:Paulbwell
thread:651514
URL: http://www.dr-bob.org/babble/20060530/msgs/652258.html