Posted by linkadge on May 9, 2006, at 17:38:39
In reply to Statistical question on SSRIs - L dL Statistics » linkadge, posted by Squiggles on May 9, 2006, at 17:24:57
I see what you are saying. Thats were a lot of people rest the case, that is that the drug provided the final umph for a person to commit suicide.
I would propose one step further, that in certain persons, an SSRI can initiate suicidal ideation where none previously existed.
The will to live (in my oppinion) is controlled by a delicate ballance between serotonin and dopamine neurotransmission. I believe that when you pharmachologically squelch dopamine you can run into big problems. Parkinsons patients have observable abnormailities in dopamine function. As a whole they tend to experience a fair share of depression. I don't think that parkinsons depression responds all that well to SSRIs. I think that sometimes, SSRI's can make both parkinsons depression, and parkinsons disorder significantly worse.
Linkadge
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