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Re: provigil discussion » tessellated

Posted by SLS on February 25, 2006, at 13:38:51

In reply to provigil discussion, posted by tessellated on February 25, 2006, at 12:33:28

> He said provigil blocked presynaptic norephinephrine (NE) autoreceptors.

I respectfully submit that your doctor's information is at least 5 years out of date. The other possibility, of course, is that mine is no longer current.

http://www.rxlist.com/cgi/generic2/modafinil_cp.htm

Modafinil does not appear to be a ligand for any NE receptor. The original work suggesting NE receptor binding by modafinil was spurious.


- Scott

 

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