Posted by SLS on February 21, 2006, at 7:45:03
In reply to Re: Question for SLS » SLS, posted by blueberry on February 21, 2006, at 5:13:29
> Thanks for your thoughts. I will look forward to more followup if you think of something to add.
> How does wellbutrin effect me? Poorly. Worsened depression and a total loss of any motivation, just want to hide in a cave. And worsened tinnitus.I would have expected it to exacerbate the tinnitus, but was hoping there was an antagonistic relationship between it and depression.
> Remeron also depresses me. And increases tinnitus.Both Remeron and Wellbutrin seem to work by ultimately increasing NE neurotransmission. However, I'm not sure either drug can be titrated in such a way as to locate a window of increased NE function that might be right for you. You could possibly have a better chance of doing this with a reuptake inhibitor or an MAOI.
> I tried nortriptyline a long time ago for just one week and don't remember much about it other than the drugged feeling and dry mouth.
I'm guessing you have already tried the SSRIs.
Nortriptyline or desipramine might be a good place to start. Many people feel a great somnolence or sedation with nortriptyline when they first start taking it. This more often than not disappears, leaving an energizing effect once it becomes effective for depression. The dry mouth might persist, but probably will not be as significant as time passes.
What were your responses to Effexor and Cymbalta?
What are the most burdensome features of your depression?Sadness?
Depressed mood?
Melancholia?
Dysphoria?
Loss of interest?
Loss of Energy?
Loss of Motivation?
Concentration or memory impairments?
Early morning awakenings?
Having the morning be the time of greatest severity?
Loss of appetite?
Loss of libido?
Irritability?
Social inhibition?
Anxiety?
- Scott
poster:SLS
thread:611554
URL: http://www.dr-bob.org/babble/20060219/msgs/611648.html