Posted by med_empowered on December 5, 2005, at 6:51:40
In reply to Re: Tell me about dopamine agonists for depression, posted by linkadge on December 4, 2005, at 18:10:16
my take on the situation is the same as linkadges--used alone, you probably wont see much (or any) mood-lifting effect. In combo with other drugs, you may see a response--perhaps turning a partial response into a more robust one, or non-response into a noticeable, significant one. I think Provigil could be interesting; it might also be worthwhile to go with something that doesn't do your usual serotonin reuptake inhibition...maybe Surmontil? Stablon (I dont know where you live..this may or may not be an option)? Buspar+antidepressant of choice+dopamine agonist might be cool. It would seem that low-dose Abilify plus an antidepressant could do some dopamine agonism that could be pretty significant.
Also...have you tried sleep deprivation? I dont know if its appropriate for you, but you might want to talk to a doc about it...*some* people get very nice results; the problem is maintaining them....I imagine an experienced doc could work out a med plan that would help maintain your results. Some surprising meds have action on dopamine...Trileptal, for instance, may have an antidepressant action due in part to some sort of dopamine-enhancing activity. Another poster mentioned opiates...that might be worth pursuing. Ultram, Temgesic, and others have proven useful in some cases of depression; some of it may have to do with the usual (ex: Ultram inhibits reuptake of some neurotransmitters), but some of it is probably due to as-yet unknown actions specific to the opiates.
Good luck!
poster:med_empowered
thread:585415
URL: http://www.dr-bob.org/babble/20051203/msgs/585676.html