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Re: How come Wellbutrin and Risperdal don't cancel

Posted by med_empowered on December 1, 2005, at 23:51:51

In reply to Re: How come Wellbutrin and Risperdal don't cancel » Deneb, posted by Larry Hoover on December 1, 2005, at 23:20:41

I don't know either, really...but it kind of makes sense. When you combine Zyprexa and Prozac, for instance, the combo increases dopamine, norepinephrine, and serotonin levels. Usually, antipsychotics decrease most (or all) of those neurotransmitters, and antidepressants only moderately increase levels of one or two. Also, if you read some old studies, you'll find that extremely low-dose *old* antipsychotics seem to do the same thing. This one study I read gave normal subjects .5mgs Haldol (very, very small dose)...their reaction times actually went *up*, not down, which is a reaction more common to a stimulant, not an antipsychotic.


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