Posted by jay on October 23, 2005, at 19:05:39
In reply to Re: MAO mice/man/anxiety/agression, posted by linkadge on October 23, 2005, at 17:24:30
> But thats the thing, the study involves mice who don't have MAO. It says that these mice are more anxious, less body weight, more agressive etc.
>
> LinkadgeYes, I think this can be explained. It's all about the up and down regulation of the pathways and receptors. At the start (which also happens to be the period drug companies are saying people may have suicidal ideation), the amines just flourish in the brain. Less maoi, more amines which over time (like how every other antidepressant works) regulates the receptors.(And hence, the lessening of suicidal ideation.) I see it like this...it's like you are 'toning' your brain, like a muscle. The receptor number may be regulated...maybe there where too many or too few. Throw in some meds that 'tone' the serotonin (like serzone, remeron, etc..) system, and ones that do the same for the dopamine system (like zyprexa, or even high dose buspar, or abilify)I think we have the potential to do SO MUCH better with meds. That is why I feel many people have success on 6 or 7 meds that all do this or block that. Doctors are just too scared to go that high with meds. Luckily, mine isn't, and no by far am I 'cured', but I am leading a life 80-90 percent more stable than just a few years ago.(Knock on wood..lol :-)
Anyhow...thats just my take..fwiw..
Jay
poster:jay
thread:570939
URL: http://www.dr-bob.org/babble/20051017/msgs/571124.html