Posted by SLS on September 13, 2005, at 10:21:50
In reply to Re: Neurogenesis, posted by linkadge on September 13, 2005, at 8:23:09
Hi Linkadge.
Thanks for the insights.
Your observations and comments are compelling. I really hope that growth factors might represent a potent therapy for depression, even if it only works in conjuction with standard antidepressants.
- Scott> Neurogeneisis need not necessarily be brand new neurons. It can mean the reestablishment of previous connections.
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> Neurogeneisis happens in all areas of the brain. In the pleasure centres of the brain too.
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> When you're depressed it may be from broken limbic circutry. When connections are restablished those feelings come back.
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> Its not the only theory.
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> But we know that growth factor injections produce similar AD effects (NT-3 NGF, BDNF, GDNF etc)
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> Did you see that 60minautes episode on parkinsons and GDNF, it was crazy. One guy coudn't move at all, but after 2 years on GDNF he was able to walk over and hope on a tractor to ride.
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> That is a parralell that I see to mood disorders. Depression is parkinsons of the limbic system, and those growth factors may be the best chance we have to walk again.
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> Linkadge
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poster:SLS
thread:553151
URL: http://www.dr-bob.org/babble/20050909/msgs/554624.html