Posted by jonh kimble on September 10, 2005, at 18:19:25
In reply to Re: Response, posted by jonh kimble on September 10, 2005, at 16:27:02
Firstly, theres a very interesting idea, imo, at the end of this post which I might make a new thread out of. Please read it if you have a second.
Well I think I'll go ahead and try the nardil. Thanks for the responses and I have some Q's. Does an antidepressant kick in like you expect a benzo to once it does? I mean I know it takes from 2 - 5? weeks for the effect to begin but is it essentially all its going to be once you notice any effect? Also what should I expect to feel? Maybe you cant really answer that one.
Now how about interactions? I take d-amphetamine 30mgs in bursts(periodically) to help with school, and to make me more social, and just plain feel good, and I have to admit, I am beggining to see isnt such a hot idea, as 45 mgs feels better than 30mgs and now 30mgs feels better than 15 did and so on. But is dex completely contradicted? The monograph says so but I know they wanna cover there butts and tend to go too far, just as they say NEVER can you drink, and I know some alcohol is fine. There are defintly others such as NO cheese while cream cheese in moderation is fine etc.
Finally, I have an interesting theory about nardils effecicy being lowered if you are a smoker(I was when I took it before) and taking ginkgo biloba. See Nardils anti anxiety effects are thought to be somewhat (at least) related to its ability to cause a large increase in brain gaba levels. Now get this. Nardils ability to enhance brain gaba levels is dependant on the pre existence of mao a and b, as phenelzine passes through these, it inhibits them but also a new compound is formed that is responsible for these effects on gaba. In other words, the more nardil passes through mao, the more gaba, is how i understand it. If mao is being inhibited any other way, this gaba effect is lost. It is also known, or at least strongly, believed that something in tobacco and something in ginkgo both have have non selective maoi activity. Considering I was smoking and taking lots of gingko back then, that may have reduced its positive effects. Take all this into account when you read this study http://www.biopsychiatry.com/phengaba.htm
Does anyone know of other common substances that could affect nardil in this or any other way? I know this was long, but Im pretty tantalized by this thought that really just came to me while typing.
Thanks, Tom
poster:jonh kimble
thread:552000
URL: http://www.dr-bob.org/babble/20050909/msgs/553335.html