Posted by 4WD on August 19, 2005, at 15:22:51
In reply to Re: Remeron blocks SSRI side effects, posted by linkadge on August 19, 2005, at 15:19:12
> Blocking the 5-ht2a receptor can block insomnia, physical and emotional anxiety, and cortisol release.
>
> Blocking the 5-ht2c repceot can block agiation, akathesia, loss of appetite, and anorgazmia.
>
>
> Blocking the 5-ht3 receptor can prevent nausia and GI upset. 5-ht3 receptor antagonists also seem to have a degree of anti-anxiety effect.
>
> Blocking the 5-ht2a/c receptors also increases frontal cortex norepinephrine and dopamine release, which could offset apathy produced by SSRI's.
>
>
> The NE-Alpha-2 angatonist is more related to the clinical action of mirtazapine. This action increases serotonin and norepinephrine release.
> This action might add AD efficacy but would not specifically reduce and SSRI side effects.
>
>
> Linkadge
>
>
>
Linkadge, you are a gold mine of information. Thank you so much. (I know you understand the feeling you get when you get home from a 2 hour drive to a pdoc appointment and realize that you have not asked a question you needed to ask).How are you doing now? Is the Ritalin trial working out?
Thank you again,
Marsha
poster:4WD
thread:543903
URL: http://www.dr-bob.org/babble/20050816/msgs/543912.html