Posted by linkadge on August 19, 2005, at 15:19:12
In reply to Remeron blocks SSRI side effects, posted by 4WD on August 19, 2005, at 14:53:14
Blocking the 5-ht2a receptor can block insomnia, physical and emotional anxiety, and cortisol release.
Blocking the 5-ht2c repceot can block agiation, akathesia, loss of appetite, and anorgazmia.
Blocking the 5-ht3 receptor can prevent nausia and GI upset. 5-ht3 receptor antagonists also seem to have a degree of anti-anxiety effect.Blocking the 5-ht2a/c receptors also increases frontal cortex norepinephrine and dopamine release, which could offset apathy produced by SSRI's.
The NE-Alpha-2 angatonist is more related to the clinical action of mirtazapine. This action increases serotonin and norepinephrine release.
This action might add AD efficacy but would not specifically reduce and SSRI side effects.
Linkadge
poster:linkadge
thread:543903
URL: http://www.dr-bob.org/babble/20050816/msgs/543911.html