Posted by linkadge on July 23, 2005, at 18:56:49
In reply to Re: Tamoxifen for the treatment of acute mania » linkadge, posted by ed_uk on July 23, 2005, at 14:27:47
That is some interesting research. It is funny since, the so called short-short varient of the serotonin gene which is significantly correlated with increased likelyhood of lifetime depressive episode is associated with several fold reducation in the activity of the serotonin transporter. Why this condition responds to SSRI's is beyond me.
I also heard that SSRI's can increase PKC activity, in a recording of a conferance heald by Dr. Manji.
So why these drugs work is beyond me, there should be more evidence for Tianeptine like you say, since it would appear to reverse the detected genetic abormaility.
Linkadge
poster:linkadge
thread:531784
URL: http://www.dr-bob.org/babble/20050723/msgs/532333.html