Posted by SLS on July 3, 2005, at 8:57:08
In reply to Re: COMT Inhibitors for mood disorder? » ed_uk, posted by rod on July 2, 2005, at 18:38:24
Hi Roland!
If you search back in the PB archives, you might find a few submissions by AndrewB who had tried a COMT inhibitor. I can't remember which one. It could have been tolcapone for all I know. I don't think he received much benefit from it. I know he abandoned it at some point.
I had thought to attack my depression using COMT inhibitors over 20 years ago before there was such a thing. It might make sense to combine MAOI + COMTI. You would cover intracelullar and extracellular catabolization of catecholamines.
- Scott
poster:SLS
thread:521642
URL: http://www.dr-bob.org/babble/20050702/msgs/522864.html