Posted by linkadge on June 15, 2005, at 6:31:59
In reply to Re: Remeron and MAOIs, posted by SLS on June 14, 2005, at 20:58:51
Would you like the name and number of my psychiatrist? He refused my request of the combination based on his experience with a number of patients who had clinically significant hypertention.
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http://home.caregroup.org/clinical/altmed/interactions/Herbs/Pausinystalia_y.htm
mechanism: TCA's can interfere with uptake of norepinephrine, and yohimbine has been shown to interact with tricyclic antidepressants in human subjects. These studies were performed to examine whether yohimbine could ameliorate TCA adverse effects such as dry mouth; however the general finding is that a mutual increase in occurrence and intensity of adverse effects takes place when TCA's are combined with Yohimbine.------------------------------------------------
While hypertention is not specifically mentioned, it is well known that alpha-2 antaonists will enhance the noradrenic effects of the medication.Since clinically meaningful hypertention can occur on effexor alone, I fully believe my psychiatrist when he says he has observed hypertention on the combination.
Linkadge
poster:linkadge
thread:512395
URL: http://www.dr-bob.org/babble/20050611/msgs/513024.html