Posted by Chairman_MAO on June 12, 2005, at 9:47:27
In reply to Nardil + Effexor...I'm going for it!!!!, posted by ace on June 12, 2005, at 1:45:31
DO NOT DO THIS. YOU ARE PLAYING RUSSIAN ROULETTE WITH YOUR LIFE. This is more dangerous than eating tyramine-rich foods on an MAOI, IMHO.
The increase in SE from phenelzine alone is enough to produce a clinical effect. If it is not, do something safer like add l-tryptophan or 5-htp, which at least has SOME documented safety in the literature. Futhermore, it could be possible that you'd be so immersed in delirium that you may not remember that you need to take the cyprohepadine (if your oral dose is even enough to truly counteract that; they use parenteral cyproheptadine in hospitals, probably). If you are going to undertake this (IMO--note the lack of an 'H' here) futile and dangerous experiment, at least have someone else around you to call 911 when your core temperature starts reading like a seismometer during a Tsunami.
If you must do this, you need a scale accurate to 1-2mg, and start at TWO MG. Even 10-20mg of Effexor could cause serotonin syndrome if you're taking a therapeutic dose of phenelzine (1mg/kg or 80% MAO inhibition).
Effexor is WAY stronger than tramadol's reuptake inhibition, which is really weak. I wish to ask, however: Have you used tramadol with Nardil safely? I've always been wondering whether that's possible despite the warnings.
Also, if tramadol works, get buprenorphine prescribed. I guarantee it will do what you are looking for. It is the MU-OPIOID agonism that likely made you feel good, NOT MONOAMINE REUPTAKE INHIBITION.
poster:Chairman_MAO
thread:511331
URL: http://www.dr-bob.org/babble/20050611/msgs/511404.html