Posted by ed_uk on June 7, 2005, at 11:43:58
In reply to Seroquel Pharmacology question, posted by chess on June 7, 2005, at 10:09:13
Hi Chess,
>serotonin 5-HT2 occupancy fell even more slowly (half-life, 20 - 27 h)
Occupancy (and therefore antagonism) of 5-HT2 receptors dropped by half after 20-27 hours.
>D2-receptor occupancy declined more slowly (half-life, 6 - 6.4 h)
It's action at D2 receptors may also be important for its anxiolytic effects.
>.......and thus that Seroquel can be taken once-a-day for anxiety?
It might be effective once daily- you'll have to try it and see!
Are you concerned that you might forget to take it if you had to take it more than once daily?
Kind regards,
Ed.
poster:ed_uk
thread:509023
URL: http://www.dr-bob.org/babble/20050606/msgs/509059.html