Posted by Larry Hoover on May 31, 2005, at 18:49:46
In reply to Re: pellets in capsules » Larry Hoover, posted by katia on May 31, 2005, at 17:03:36
> > > > I can only speculate. That is an explanation that fits the circumstances. Maybe they fill the capsule in sequence, e.g. 1/3 rapid release, 1/3 delayed release, 1/3 extended release. If you didn't know to mix them up before you separated them into portions, you'd conceivably have different formats in each little pile you made.
> > >
> > > Larry,
> > > The way you just speculated on Effexor above, do you know if Cymbalta is the same speculation? I want to take only a few pellets a day.
> > > Thanks
> >
> > As far as I know, all the Cymbalta pellets are the same. They're enteric coated, to get them past the stomach acid intact. They're not XR formulated. Just plain enteric coating.
> >
> > Lar
> >
>
> Hi Lar,
> That's not what I was referring to. I was referring to the above statement of yours "a 1/3 is....etc.". I worry about splitting the pills up because of this.That was meant only to apply to Effexor XR, and only because the earlier poster had noted a difference in efficacy, and was seeking an explanation for same. I was speculatively offering a *possible* mechanism, because of the physical chemistry that is involved in XR specifically.
> Do you know if each pellet could be different, therefore not an accurate dose each time??
> Thaks
>I believe all the Cymbalta pellets can be considered to be identical. 10 Cymbalta pellets in one pile would be the same as any 10 Cymbalta pellets in another pile. Any difference would be too small to be of any significance.
The microencapsulation technology for the Effexor XR and Cymbalta pellets are quite different, so the implications are also quite different.
Lar
poster:Larry Hoover
thread:504288
URL: http://www.dr-bob.org/babble/20050527/msgs/505978.html