Posted by darkhorse on May 12, 2005, at 5:22:22
In reply to Re: Clomipramine + prozac = HELP:!! » ed_uk, posted by 4WD on May 11, 2005, at 22:28:58
>
>
> Ed,
>
> Would this be true for Celexa plus nortriptyline as well? I.e. would Celexa increase blood levels of nortriptyline? I am on 25mg nort and 10mg Celexa. I desperately need the anxiolytic effect of the nortr., asked my pdoc if I should go up on the dose, he said no but then my 15 minutes were up and I couldn't ask why not. I am also taking Inderal for anxiety and I fear that it will cancel out the effects of the nort. since inderal blocks norepinephrine in the brain, doesn't it?
> I couldn't ask him about that either. I did ask if it would contribute to my depression and he said we'd just have to wait and see.
>
> This board is where I get my questions answered = not from the guy I pay money to.
>
> MarshaHi,
In my experience, there was no problem at all with TCA + Citalopram.SSRIs' that most likekly to affect TCA blood levels are in this order :
-Fluvoxamine : can raise TCA's in a toxic level (except Nortriptyline and desipramine).
-Paroxetine and Fluoxetine : Also raise them,so TCA has to be taken at lowest dose(10mg), then increase slowely.
- Sertraline : raise TCA's but to a much lesser degree(no major problem)- Citalopram,Escitalopram & Venlafaxine : their effect on TCA's are minimum.(no problem!)
-(All medications mentioned I've already tried them,so this is my experience more than what books say!)
*I'm sure ED has much more input and would be a pleasure reading his comments.
Just my own experience, nothing more,nothing less!!!
Best Regards.
DH.
poster:darkhorse
thread:494252
URL: http://www.dr-bob.org/babble/20050510/msgs/496768.html