Posted by Racer on March 20, 2005, at 20:59:09
In reply to difference between EffexorXR and Cymbalta?, posted by chess on March 19, 2005, at 10:45:21
Aside from the obvious differences -- they're different drugs, different molecular structures, etc -- there is a difference in how they affect neurotransmitters. Both are selective serotonin and norepinephrine reuptake inhibitors, but Cymbalta is more balanced: it inhibits the reuptake of both more evenly at all doses. Effexor changes its profile at different dosages: lower doses target serotonin, with progressively higher doses adding more NE to the mix.
Hope that helps.
poster:Racer
thread:472786
URL: http://www.dr-bob.org/babble/20050317/msgs/473361.html