Posted by Optimist on March 16, 2005, at 22:31:32
Hi everybody,
Things are going much better lately. I've been on Parnate for 4 weeks now, the last two at 100mg per day. I hadn't noticed too much of a response until I started experimenting with some vitamins/minerals and then things made a huge turn for the better.
I've recently added some supplements to my regimand but what I feel has made the most difference is the addition of the vitamins, B6, B12, and folic acid. Within a couple days my energy has greatly improved as well as my disposition. I had heard before that B12 and folic acid can help antidepressants do their job more effectively if you're deficient in them. That may have been the case with me. I'm currently taking, 200mg B6, 1000mcg B12, and 1000mcg folic acid. It basically feels like night and day.
I was doing a internet search and some of the signs/symptoms I have seemed to keep coming up. Tinnitus, hearing loss, premature greying of hair, ridges on my fingernails, and fatigue. They may be indicative of a B12 deficiency. The greying of my hair and fatigue started stortly after I took accutane at age 17. Accutane is supposedly known to cause the depletion of B12 I just read after doing a google search. I've had ridges on my finger nails since I was an early teenager, and the tinnitus/hearing loss I've had for the last 3 years or so. It's not definitive of course but a good working theory at this point, especially since I feel so much better as of late. It could also be the folic acid and B6 that are making me feel better, or some other unknown factor. It's also possible the Parnate magically kicked around the same time I started the B vitamins. It's hard to definitely say at the moment without proper experimentation. I don't really care as long as it's gone and it stays that way. :)
So for now I have 100 remission of my depressive symptoms and pretty much 90-95% of my social anxiety is gone which is damn pretty good at this point.
One of my own personal theories of AD poopout is the vitamin/mineral deficiencies drugs can cause over time. It may be possible that if a drug stops working or doesn't work in the first place it may be because one is missing a necessarily enzyme/cofactor for the medication to do it's job properly.
I'm also going to try and get ahold of some TMG(trimethyl-glycine) to perhaps further aid my response. If it's related to homocysteine levels and SAMe then it's possible it cause even more improvement. I just bought some DMG (there wasn't any TMG) today but after doing some further research I'm not as optimistic about it's efficacy. I'll have to see if I can find another supplier somewhere. It's supposed to work synergistically with B6, B12, and folic acid for reducing homocysteine and increasing SAMe naturally.
Hope everyone is well,
Brian
poster:Optimist
thread:471914
URL: http://www.dr-bob.org/babble/20050312/msgs/471914.html