Posted by Elroy on March 13, 2005, at 20:46:56
In reply to Re: 4 Wks off Effexor-/joint pain, posted by zach on May 27, 2002, at 11:49:20
Don't know if you're still catching these posts, but there is a VERY definite connection between Effexor and prostatitis. Run a search on this board and you'll find some quotes right from the manufacturer's warning labels. I was on it for about three days last summer (I have a prostate that's very sensitive to irritating substances like that - and it went crazy)!
BTW, Cymbalta is the same way, it's just more subtle and takes quite a bit longer for the prostatitis to surface (if you afre prone to that side effect). I lasted about ten days on the Cymbalta.
Apparently has to do with both of them being SSNRIs that are also increasing Norepinephrine levels as well as the serotonin leevls - and it's the former (apparently) that creates the inflammation with the prostate and / or inflammation of the urinary tract.
Even would need to be cautious with something like amino acid DLPA and deprenyl combination as DLPA can cause release of Norepinephrine and cause prostatitis flare up.
Only about 5% of prostatitis cases are believed (by some authorities) to be caused by bacterial infection and yet the first thing most uros do is to prescribe very strong antibiotics!
Elroy
> Wow! Well... I've been on Effexor XR for nearly one year. It has helped significantly decrease the level as well as the frequency of my depressive episodes. I am concerned (very much so) about the joing pains. From the beginning I have noticed a tightening of the jaw muscles. I had to get a mouth guard for when I sleep. I also wake up most mornings with sore muscles in my forearms, which I presume is from clenching my hands. I did not have either of these problems before one year ago. Recently, I was diagnosed with tendonitis of the wrists as well as arthritis of the knees. I take aspirin, and it helps but does not cure. I am 27 years old, and a professional musician. I also am a competing martial arts practitioner. If I knew for certain that there was a corrolation between joint pain and Effexor XR I would have to rethink my decision to take it. I started Effexor as a response to the sexual side-effects of Celexa. By the way, I also have been diagnosed with prostatitis. It has also crossed my mind that Bactrim could be causing or agrivating joint pains. I can't help wondering what the relationship between the medications and the physical ailments is. I did bloodwork to test for Reiter's syndrome. My HLAB-27 was positive. Remember, I am only 27, and in excellent shape. I stretch daily before and usually after I excercise. If anyone has any information for me please email me at zachburd@yahoo.com. This is my personal spam-free email address. Please respect this, and keep me off all lists. Thank you. -Zach
poster:Elroy
thread:13781
URL: http://www.dr-bob.org/babble/20050312/msgs/470655.html