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Re: My little theory on reboxetine.Therapeutic window? » banga

Posted by ed_uk on March 6, 2005, at 11:08:53

In reply to Re: My little theory on reboxetine.Therapeutic window? » sabre, posted by banga on March 6, 2005, at 2:59:57

Hi,

Desipramine is a potent norepinephrine reupake inhibitor.
A *very* weak serotonin reuptake inhibitor.
A weak antihistamine.
A weak antagonist of mACh receptors ie. it's antimuscarinic, 'anticholinergic'.

>Does this mean that the desipramine also affects 5ht2a receptors??

Slightly, it's a weak antagonist- it has a lower affinity for this receptor than other TCAs.

Ed.



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