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Re: what is the diff between NA/CA channels

Posted by sdb on February 10, 2005, at 15:01:01

In reply to what is the diff between NA/CA channels, posted by linkadge on February 9, 2005, at 16:58:00

It depends where you block Na/Ca channels in the body. The physiology of the hohle system is very complicated. In the kidneys it would cause diuresis. In the gastrointestinal tract it would hamper resorption of substances and water. In the brain. In the heart it would block fast Na channels and therefore changing timing of action potential. Na and Ca are essential metals also in the propagation of actionpotential in dendrites, axones. Ca is also trigger of muscle contraction (sarcoplasmatic reticulum) and plays an important role in releasing neurotransmitters in synapses. Blocking na/ca directly would cause tremendous side effects.
Na/ca plays an essential role in the brain.
But it is only partly understood.


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