Posted by aazospiro on February 2, 2005, at 0:45:03
In reply to Re: Are any of these new GABA meds effective? » 3 Beer Effect, posted by Michael Bell on January 31, 2005, at 4:59:05
Ahmmm correction there mister,
Klonopin [Clonazepam] differs from the rest of the benzodiazepines in that in is a partial agonist at the BDZ receptors.
Interesting thing about thses neurotransmitters [from my many many readings] is that they display what I refer to as the "see-saw effect"
Specifically, GABAergic drugs loose their euphorigenic effects, calming properties which quickly turns to severe irritabilitywith chronic use, but add a dopaminergic agent like selegiline or Sinemet or even better a stim and its all back again like if you used it for the first time.
And while on the subject of stimulants, all the chit chat about glutamate antagonists like DXM being used for stim tolerance [which I cant dispute] hasn't anyone considered the effects that T-4 or T3 have on the responsiveness of adrenergic/ dopaminergic receptors. Apparently even though no receptor density changes are evident, the response is augmented and only very tiny doses are needed of the latter.
Certaintly food for thought
poster:aazospiro
thread:448915
URL: http://www.dr-bob.org/babble/20050128/msgs/451474.html