Posted by SLS on January 29, 2005, at 22:58:03
In reply to Metyrapone with/without hydrocortisol???????, posted by bipolarspectrum on January 29, 2005, at 20:54:16
> Hi,
> I think I'm doing to ask my pdoc if I can begin metyrapone this monday... check out pubmed, there has been 2 large add-ons studies with it resulting in success... i will probably try it alone, but a study with metyrapone alone for depression used some hydrocortisone... I'm not quite sure what the hydrocortisone was used, I assume its to maintain cortisol levels.. any opinions?
> bps
I brought up metyrapone to my doctor at my last visit. He seemed receptive, and he will probably do some homework on it before I see him next. I saw the study in which the hydrocortisone was used to offset the metyrapone. It sounded like a good idea. I'm really not sure because I don't have any data to compare it to. I just don't know if it is necessary. I guess I don't want to be bothered with it. If you recall, some of the studies used a combination of metyrapone and another cortisol synthesis inhibitor. There has been a lot of work done with ketoconazole. Is there any reason why you are not going to try it first?I didn't think one could buy metyrapone from a pharmacy in the amount necessary to use it therapeutically in the US. How are you going to get it?
- Scott
poster:SLS
thread:449948
URL: http://www.dr-bob.org/babble/20050128/msgs/449998.html