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TCAs and Weight Gain

Posted by tygereyes on January 3, 2005, at 0:35:43

I'm sure this has been asked before, but which tricyclic antidepressant is the least likely to cause weight gain?

I was just released from an inpatient eating disorders unit and I'm in the early stages of recovery from anorexia nervosa, and I think Nortriptyline is making my constant hunger even worse. I know it's caused me to gain weight in the past.

And I have to take a tricyclic because I have Interstitial Cystitis, which is activated by SSRIs. It also activates mood stabilizers, to a lesser degree, so a tricyclic is necessary in order to keep the bladder problems caused by Trileptal (my other med) in check.

I've heard that Desipramine is fairly neutral in terms of weight gain. Is this true? It's so difficult to find information on the tricyclics, because research is so focused on the newer AD drugs.


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poster:tygereyes thread:437085
URL: http://www.dr-bob.org/babble/20041228/msgs/437085.html