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Re: grapefruit (fruit and juice) ??????????LARRY » Fallen4MyT

Posted by Larry Hoover on December 26, 2004, at 19:22:27

In reply to Re: grapefruit (fruit and juice) ??????????LARRY, posted by Fallen4MyT on December 26, 2004, at 17:45:37

> So if I take a valium and drink the grapfruit juice I will FEEL the valium more and longer??????? Thanks ahead for the help on this

Diazepam is a little bit different than alprazolam. There are four different metabolic routes for diazepam. Four different enzymes, and only of them blocked by grapefruit juice. The metabolites of diazepam have some activity, too, so it's pretty hard to say just what the outcome would be. But, yes, in general, the effect of the diazepam would be intensified and lengthened. To what extent is not easily predicted. The difference might be too small to notice.

Lar

 

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poster:Larry Hoover thread:434329
URL: http://www.dr-bob.org/babble/20041223/msgs/434423.html