Posted by pablo1 on December 13, 2004, at 18:04:02
In reply to SSRI/dopamine antagonism- easier to read/print ver » raybakes, posted by tealady on December 13, 2004, at 17:50:52
So, I'm really not following this but would some of this 'body's response' business have to do with the month it supposedly takes to adjust to SSRI's? I've been on Zoloft about a month & am beginning to get extra sensitive to my other dopamine meds and Zoloft already has quite a bit of dopamine effect. As a consequence, I'm a bit wired & not sleeping well. I also quit drinking but initially that just made me sleep more.
Effexor messed up my sleep patterns making me sleepy in the day & waking repeatedly at night which seemed more of a norepenephrine thing and when I went off Effexor after 6 weeks I got this incredible dopamine rebound for a couple weeks. It was obvious that it had been sapping my dopamine away & I felt it come back stonger than I ever felt. Agh, this stuff is just too complicated!
I don't know what is supposed to change after a month on SSRI's but I feel them right away when starting as a sort of sedating effect. I think all that's supposed to change is the side effects go away & the calming continues but I don't know. If I'm not feeling any actual improvement after 50 zoloft 50mg, I'm giving this up too, especially with the sleep disturbances.
poster:pablo1
thread:428740
URL: http://www.dr-bob.org/babble/20041211/msgs/429035.html