Posted by linkadge on November 28, 2004, at 1:06:00
In reply to Re: Scott ,another thing to add., posted by denise1904 on November 26, 2004, at 9:07:51
Lithium is a 5-ht autoreceptor antagonist. Ie it blocks the serotonin thermostat so to speak, allowing more to be released. In this method it rapidly increases serotonin content. Pindolol is also a 5-ht autoreceptor antagonist, but has not gained the same recognition as an augmentation agent, perhaps because it does not share other properties of lithium.
Lithium alone increases BDNF, NGF,serotonin, decreases cortisol, and glutamate. It is also trophic to the grey matter and hippocampus.
Drawbacks, lithium can be a downer. It saps your brain of mood brightening inositol. Perhaps lithium + inositol would be a better augmentation agent.
I don't really love lithium myself, but its my only attempt to salvage my brain. I'm trying to do a lithium and exercise only routine.
Denise: I would add folic acid (1mg) to your paxil. I know it sounds simple, but folic acid turned my celexa from a nonresponce to a responce for over a year. Inositol can also increase the responsivness of gaba and serotonin receptors.
At one point I was able to down my celexa from 30mg to 10mg by taking 2g of inositol daily. Wherease other attempts to decrease celexa were in vain.
Another thing that really helped me was to eat loads of turkey and drink milk, tryptohpan loaded foods.
Also omega 3 plumps up the serotonin receptors. The serotonin receptors need omega 3 to work more flawlessly.
I would take your paxil +Folic Acid, Inositol, Omega 3, and high tryptophan diet. I think this would *really*
boost the effectivness of your paxil.P.S. I'm in a bit of a positive mood cause I did a total nights sleep deprivation. This works for me when nothing else works.
Linakdge
poster:linkadge
thread:419276
URL: http://www.dr-bob.org/babble/20041123/msgs/421167.html