Posted by Larry Hoover on November 21, 2004, at 9:25:43
In reply to Larry: What is your opinion on accutane?, posted by stresser on November 19, 2004, at 20:14:53
> Larry,
> I really only meant that intimidating comment as a compliment,I'm sorry if I offended you, I didn't want that to happen. I value having you on the board and consider it a privilage.Thank you for your kind words, and apology. I wasn't offended. I know I intimidate without ever meaning to. Trust me to work through things with you, okay? Just keep asking questions, and I'll try and answer them to your satisfaction.
> I don't seem to have much of a reaction to any anti-depressants, or at least the different medications I have tried.
If you also mean no side-effects, too, you may be a rapid metabolizer. That's quite the opposite effect to most of the people who entered into this thread. You might deactivate and excrete the drug so fast that is has no chance of accumulating in your blood to effective levels. If you can get a doctor to consider helping you (it would take some direct supervision and probably some fairly expensive bloodwork), you might find that purposely using a liver enzyme inhibitor would enhance the drug effect. For example, ketoconazole, the antifungal drug, near totally inhibits 3A4. Maybe that's the kind of thing you need, along with an antidepressant, to get some effect.
Also, you might consider St. John's wort. It works by many different and unique mechanisms that may not be affected by your liver function.
> I do have a question concerning accutane, because I and my daughter have taken it in the past. Let me tell you exactly what has happened. My daughter took Accutane three years ago, and it worked very well....until she stopped taking it. Her face broke out about three months after she she took her last pill, so the doc. put her on another round. I have ALWAYS had trouble with acne, and at 41, (at that time) was tired of the oily face and teenage break-outs. I decided to take it also, and he put us both on the generic form of accutane. Seven months on the generic form went very well, and we both went off with great results and very little side-effects. Some depression, but that was there anyway, so who knows about that one. It was probably six months after we both went off the generic, that she started to break-out horribly AGAIN, and after anti-biotics and Retin A once agian, she is back on the real Accutan, and taking one pill twice per week. That is keeping her acne under some control, but if she lets off, it returns like chicken pox! She did take many anti-biotics and nothing worked for her. Myself, the oily skin is back, and I am having those nasty break-outs and wonder if the generic was worth my trip to the pharmacy. Honestly, I don't think my body responds to medication very well, and I think I have passed it on to my daughter. Is that possible? Have we just always taken the wrong medications for our bodies? What is your opinion? -L
Accutane is due for some serious attention. It can be very toxic in some people. That aside, the fact that it works so well for you suggests that you might consider just using it until after menopause. That should end the problem for you. I'd have to look more closely at how it works. I'm not really sure.
Lar
poster:Larry Hoover
thread:417092
URL: http://www.dr-bob.org/babble/20041118/msgs/418578.html