Posted by Ritch on November 5, 2004, at 9:57:10
In reply to Re: Wellbutrin Metabolites » Ritch, posted by smith562 on November 4, 2004, at 16:45:22
> Hey Mitch ... Does the metabolites of wellbutrin have strong norepiphrine and dopamine reuptake properties? I too have read that the parent compound does little reuptake and actually inhibits dopamine in part of the brain. But the active metabolites supply the medication its efficacy.
>
> Smith
>
>I don't know about what they actually are *doing* for sure (the parent and the metabolites), but I do know that when I start taking WB I seem to get a clear improvement in energy levels and don't feel very anxious at all. But after a few days/weeks anxiety begins to build up. So, in my case it seems the parent compound seems to be beneficial, while the metabolites appear to be troublesome.
poster:Ritch
thread:410787
URL: http://www.dr-bob.org/babble/20041103/msgs/412068.html