Posted by Kristel on October 24, 2004, at 5:47:28
In reply to MAOIs decrease density of DA receptors- KingVultan, posted by karaS on October 24, 2004, at 5:09:36
> Todd,
>
> Thought you might like to see this abstract which seems to confirm what you've been saying. Here's the key sentence from it:
>
> "MAOI antidepressants induced a decrease in the density of both D1-like and D2-like DA receptors."
>
> Here's the link:
>
> http://www.chocolate.org/peadep.htm
>
> KaraAnd that is a negative thing to happen ?!!
In fact the opposite might be true. Decrease in receptos density mean down-regulation which is thought of as the anti-depressant mechanism of these drugs. Decrease in density means increase in sensitivity of the receptors.
poster:Kristel
thread:406550
URL: http://www.dr-bob.org/babble/20041024/msgs/406555.html