Posted by researcher437 on September 5, 2004, at 16:32:24
In reply to Which meds increase dopamine/energy?, posted by craig getty on August 5, 2004, at 23:04:03
> Can someone tell me which meds increase dopamine and are legal in the U.S.?
>
> I'm currently on Wellbutrin and Effexor. I think more dopamine is what I need for my dysthymia, daytime sleepiness, and low motivation.
>
> I have been on Wellbutrin (350 mg) for the last several months but was still tired and low in motivation. So, my pdoc added Effexor. I have been on it for a month (1st week @ 75mg and since then 150 mg). Effexor was supposed to give me more energy, but so far I think it is making me more tired - maybe because I always wake up in the middle of the night and can't fall back asleep.
>
> Provigil and Ritalin have not worked for me in the past (I developed a quick tolerance), so my pdoc is reluctant to try another stimulant. I've even tried ginseng, ginko, and vitamin B for energy, but these don't work.
>
Psychostimulants (adderall.dextroamphetamine,ritalin) typically increase dopamine levels;however there is a danger of addiction.Strattera increase dopamine in the mesocortical tract but much less so in the nucleus acumbens;
less danger of addiction, but will not make you feel better either.Try adding some of the neuromodulators(Piracetam,Aniracetam,Pramiracetam)along with centrophenoxime.
Supplements that are known to increase dopamine are L-Thyrosine ,NADH,L-theanine,
CDP-Choline,yohimbine,Phophatidylserine.Selegiline 5mg twice a day prevents the breakdown of dopamine but BEWARE ADVERSE INTERACTIONS with drugs or foods.
I have dysthymia,but what works for me may not work for you,due to biological variation.
Here is what works for me:
Selegiline 15 mg before breakfast
Provigil 200 mg before breakdast
NADH 5 mg before breakfast
Piracetam 1600 mg twice a day
Aniracetam 750mg twice a day
Centrophenoxine 3 a day
L-theanine 600 mg a day
Yohimbine 5 mg a day
Picamillon 3 a day
MethylPhenidate 20 mg if I feel sleepy in the afternoon
Alprazolam 1 mg at bedtimePramiracetam helps against apathy but is currently unavailable for the most part.
(I don't take thyrosine because of a strong history of prostate cancer in my family;induction of thyroxine hydroxylase may promote cancer growth)
I also avoid excess carbs because a high carb diet promotes increased serotonin
This is a high power dopamine regimen;I know I am taking too much if I start talking too much(I am naturally a very quiet guy).
In spite of all that Dopamine I still have difficulty with boring daily chores such as cleaning or doing dishes.Pramiracetam seems to be the only thing that helps me with those but I am out of PramiracetamLikely side-effect of this regimen is dizziness at the beginning;one needs to decrease the dose if that happens.
There should be no problem mixing selegiline and Wellbutrin;however Efexor has some SSRI properties
and combination with selegiline could lead to serotonin syndrome.
Wellbutrin and selegiline did not work for me so i dropped the Wellbutrin and went to the racetams.Make sure you know what you're doing when taking meds and supplements.
Disclaimer
This is only given as information NOT as recommendation.
researcher437
poster:researcher437
thread:374543
URL: http://www.dr-bob.org/babble/20040904/msgs/386797.html