Posted by Shawn. T. on August 21, 2004, at 19:11:48
In reply to Re: A question for Chemist... » Shawn. T., posted by chemist on August 21, 2004, at 18:26:54
The abuse potential for propoxyphene is certainly less than for drugs like morphine or hydrocodone. I would assume that the abuse potential varies among individuals to a greater degree than for more potent mu opioid receptor agonists. Where did you read that propoxyphene is a kappa receptor agonist? I believe that the drug does affect these receptors but only at concentrations that are much higher than therapeutic concentrations. For example, see http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6151117
Isn't (+)-alpha-propoxyphene a synonym for propoxyphene? See http://www.cdc.gov/niosh/rtecs/el2dc6c0.html
Shawn
poster:Shawn. T.
thread:380358
URL: http://www.dr-bob.org/babble/20040821/msgs/380546.html